Management of Airway Remodeling in a Mouse Model of Allergic Airways Inflammation Using Extracellular Vesicles from Human Bone Marrow-Derived Mesenchymal Stromal Cells
نویسندگان
چکیده
HIGHLIGHTS Extracellular vesicles (EV) from human bone marrow were able to reduce airway inflammation in a mouse model. Treatment applied by Intratracheal injection was more effective than systemic administration caudal vein injection. IT of EVs appears act therapeutically restoring the basal BAL cell counts and attenuating early lung remodeling.
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ژورنال
عنوان ژورنال: Brazilian Archives of Biology and Technology
سال: 2022
ISSN: ['1678-4324', '1516-8913']
DOI: https://doi.org/10.1590/1678-4324-2022200620